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Understanding channel tropism in traditional Chinese medicine in the context of systems biology

Ping Liu, Songlin Liu, Gang Chen, Ping Wang

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 277-279 doi: 10.1007/s11684-013-0273-3

Abstract: Results showed that this theory and systems biology have a similar holistic viewpoint.Systems biology could provide novel insights and platform in the study of channel tropism.

Keywords: systems biology     channel tropism theory     traditional Chinese medicine     application    

Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction

Hong LI,Ziding ZHANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2,   Pages 102-112 doi: 10.15302/J-FASE-2016100

Abstract: and transcriptomics) has provided a great opportunity to explore plant–pathogen interactions from a systems

Keywords: plant–pathogen interactions     systems biology     omics     plant immunity     protein–protein interaction     network    

Dendritic cell vaccines in cancer immunotherapy: from biology to translational medicine

Hongmei Xu, Xuetao Cao

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 323-332 doi: 10.1007/s11684-011-0172-4

Abstract:

Comparative lipidomic analysis of

Bin QIAO, Hong-Chi TIAN, Ying-Jin YUAN

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4,   Pages 461-469 doi: 10.1007/s11705-012-1223-3

Abstract: Variations in the composition and level of phospholipids (PLs) in yeast cells during industrial ethanol fermentation processes were analyzed. A comparative lipidomic method was used to investigate the changes in total cellular PLs during continuous and fed-batch/batch processes. The phospholipid metabolism in yeast changed during both processes, mainly due to the presence of long-chain poly unsaturated fatty acids (PUFA) that contained phosphatidyglycerol (PG), phosphatidylethanolamine (PE) and phosphatidylserine (PS). The complexity of the media affected the growth of the yeast and the membrane composition. Yeast incorporated lots of exogenous saturated and PUFAs from the feedstock during the fermentations. During the continuous fermentation, there was an increase in PLs with shorter chains as the fermentation progressed and early in process there were more long-chains. During the fed-batch/batch process, the PG species increased as the fermentation progressed. This is probably due to an inositol deficiency in the earlier part of the fermentation.

Keywords: lipidomics     systems biology     phospholipids     stirred-tank     saccharomyces cerevisiae     biorefinery    

Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

Frontiers of Medicine doi: 10.1007/s11684-023-1044-4

Abstract: As of May 3, 2023, the coronavirus disease 2019 (COVID-19) pandemic has resulted in more than 760 million confirmed cases and over 6.9 million deaths. Several patients have developed pneumonia, which can deteriorate into acute respiratory distress syndrome. The primary etiology may be attributed to cytokine storm, which is triggered by the excessive release of proinflammatory cytokines and subsequently leads to immune dysregulation. Considering that high levels of interleukin-6 (IL-6) have been detected in several highly pathogenic coronavirus-infected diseases, such as severe acute respiratory syndrome in 2002, the Middle East respiratory syndrome in 2012, and COVID-19, the IL-6 pathway has emerged as a key in the pathogenesis of this hyperinflammatory state. Thus, we review the history of cytokine storm and the process of targeting IL-6 signaling to elucidate the pivotal role played by tocilizumab in combating COVID-19.

Keywords: SARS-CoV-2     COVID-19     cytokine storm     interleukin-6     tocilizumab    

Designer enzyme for green materials innovation: Lactate-polymerizing enzyme as a key catalyst

Seiichi Taguchi

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1,   Pages 139-142 doi: 10.1007/s11705-017-1636-0

Abstract: typical topic of synthetic biology.

Keywords: synthetic biology     enzyme evolutionary engineering     polyhydroxyalkanoate    

Correlation between cold and hot pattern in traditional Chinese medicine and gene expression profiles in rheumatoid arthritis

Miao Jiang, Cheng Xiao, Gao Chen, Cheng Lu, Qinglin Zha, Xiaoping Yan, Weiping Kong, Shijie Xu, Dahong Ju, Pu Xu, Youwen Zou, Aiping Lu

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 219-228 doi: 10.1007/s11684-011-0133-y

Abstract: In the present study, we combine genome-wide expression analysis with methods of systems biology to identify

Keywords: gene expression profile     pathway     rheumatoid arthritis     traditional Chinese medicine     systems biology    

MicroRNAs and lung cancers: from pathogenesis to clinical implications

Ji Qi, David Mu

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 134-155 doi: 10.1007/s11684-012-0188-4

Abstract:

Lung cancer is the leading cause of cancer-related deaths in the US and worldwide. Better understanding of the disease is warranted for improvement in clinical management. Here we summarize the functions of small-RNA-based, posttranscriptional gene regulators, i.e. microRNAs, in the pathogenesis of lung cancers. We discuss the microRNAs that play oncogenic as well as tumor suppressive roles. We also touch on the value of microRNAs as markers for diagnosis, prognosis and the promising field of microRNA-based novel therapies for lung cancers.

Keywords: lung biology     lung cancer     microRNA    

Genome reprogramming for synthetic biology

Kylie Standage-Beier,Xiao Wang

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1,   Pages 37-45 doi: 10.1007/s11705-017-1618-2

Abstract: ability to go from a digitized DNA sequence to a predictable biological function is central to synthetic biologydevelopment of new programmable tools to reengineer genomes has spurred myriad advances in synthetic biologypalindromic repeats enable RNA-guided rational redesign of organisms and implementation of synthetic gene systems

Keywords: CRISPR     genome engineering     synthetic biology     rational design    

Current status and prospects of reliability systems engineering in China

Frontiers of Engineering Management 2021, Volume 8, Issue 4,   Pages 492-502 doi: 10.1007/s42524-021-0172-2

Abstract: This study provides a systematic overview of the advent and evolution of reliability systems engineering

Keywords: reliability     effectiveness     model-based systems engineering     reliability systems engineering    

Floating production storage and offloading systems’ cost and motion performance: A systems thinking application

Rini NISHANTH, Andrew WHYTE, V. John KURIAN

Frontiers of Engineering Management 2018, Volume 5, Issue 3,   Pages 357-368 doi: 10.15302/J-FEM-2018022

Abstract: Systems thinking gives a unique opportunity to seek a balance between FPSO technical performance(s),Systems thinking has been used to explain the interaction of problem variables; resultantly this paper

Keywords: FPSO     LCCA     spread/turret-mooring     DeepC     cost     motion     soft-systems    

TRANSFORMING CHINESE FOOD AND AGRICULTURE: A SYSTEMS PERSPECTIVE

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 1,   Pages 4-15 doi: 10.15302/J-FASE-2023493

Abstract:

● The goals of Chinese food and agriculture have shifted from grain self-sufficiency to diversified goals, including protecting natural resources, reducing pollution and greenhouse gas emissions, and improving food safety and nutrition.

Keywords: food systems     food security     nutrition     climate change    

Recent advances in fruit crop genomics

Qiang XU,Chaoyang LIU,Manosh Kumar BISWAS,Zhiyong PAN,Xiuxin DENG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 1,   Pages 21-27 doi: 10.15302/J-FASE-2014002

Abstract: In recent years, dramatic progress has been made in the genomics of fruit crops. The publication of a dozen fruit crop genomes represents a milestone for both functional genomics and breeding programs in fruit crops. Rapid advances in high-throughput sequencing technology have revolutionized the manner and scale of genomics in fruit crops. Research on fruit crops is encompassing a wide range of biological questions which are unique and cannot be addressed in a model plant such as . This review summarizes recent achievements of research on the genome, transcriptome, proteome, miRNAs and epigenome of fruit crops.

Keywords: fruit crops     fruit biology     gene function     genomics    

TRANSFORMATION OF FOOD SYSTEMS: HOW CAN IT BE FINANCED?

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 1,   Pages 109-123 doi: 10.15302/J-FASE-2023483

Abstract:

● The analysis of financing for the transformation of food systems

Keywords: financial markets     food systems     development financing     consumer expenditures     public budgets     Sustainable    

To Hold the Economical Time of Biology,to Practicea Positive View of Happiness

Gan Ziheng

Strategic Study of CAE 2007, Volume 9, Issue 2,   Pages 5-11

Abstract:

As predicted,the global economy is stepping into a so called "biological economy" by 2020, which can be explained as economy mainly dominated by biological technologies. The essay discusses the proposition, definition, classification and characteristic of biological economy, also, the importance of positive view of happiness in a biological economy condition and the reason for emphasizing people's happiness achieving,and the definition of happiness philosophy. It also discusses which views of happiness should be recommended and how to practice a positive view of happiness in the scientific and technological circle in China.

Keywords: biological economy     happiness     positive view of happiness    

Title Author Date Type Operation

Understanding channel tropism in traditional Chinese medicine in the context of systems biology

Ping Liu, Songlin Liu, Gang Chen, Ping Wang

Journal Article

Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction

Hong LI,Ziding ZHANG

Journal Article

Dendritic cell vaccines in cancer immunotherapy: from biology to translational medicine

Hongmei Xu, Xuetao Cao

Journal Article

Comparative lipidomic analysis of

Bin QIAO, Hong-Chi TIAN, Ying-Jin YUAN

Journal Article

Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

Journal Article

Designer enzyme for green materials innovation: Lactate-polymerizing enzyme as a key catalyst

Seiichi Taguchi

Journal Article

Correlation between cold and hot pattern in traditional Chinese medicine and gene expression profiles in rheumatoid arthritis

Miao Jiang, Cheng Xiao, Gao Chen, Cheng Lu, Qinglin Zha, Xiaoping Yan, Weiping Kong, Shijie Xu, Dahong Ju, Pu Xu, Youwen Zou, Aiping Lu

Journal Article

MicroRNAs and lung cancers: from pathogenesis to clinical implications

Ji Qi, David Mu

Journal Article

Genome reprogramming for synthetic biology

Kylie Standage-Beier,Xiao Wang

Journal Article

Current status and prospects of reliability systems engineering in China

Journal Article

Floating production storage and offloading systems’ cost and motion performance: A systems thinking application

Rini NISHANTH, Andrew WHYTE, V. John KURIAN

Journal Article

TRANSFORMING CHINESE FOOD AND AGRICULTURE: A SYSTEMS PERSPECTIVE

Journal Article

Recent advances in fruit crop genomics

Qiang XU,Chaoyang LIU,Manosh Kumar BISWAS,Zhiyong PAN,Xiuxin DENG

Journal Article

TRANSFORMATION OF FOOD SYSTEMS: HOW CAN IT BE FINANCED?

Journal Article

To Hold the Economical Time of Biology,to Practicea Positive View of Happiness

Gan Ziheng

Journal Article